CHAPTER ONE
INTRODUCTION
1.1 Background of the Study
A successful drug that passes the hurdles of clinical trials to gain approval and a strong market position must exhibit a delicate balance of biological and physicochemical properties. Such a compound must, of course, be potent against its intended physiological target(s); however, it must also have appropriate pharmacokinetics to reach the site of the target at a sufficiently high concentration and for an appropriate duration via the intended route of administration. Furthermore, for the compound to be safely administered, it must avoid unintended side-effects, drug-drug interactions and nonspecific or idiosyncratic toxicities at the therapeutic dose. The goal of drug discovery is to identify a successful compound as efficiently as possible. But, as the history of drug discovery has proved, this is a challenge of significant proportions [1].
Terms of Use: This is an academic paper. Students should NOT copy our materials word to word, as we DO NOT encourage Plagiarism. Only use as a guide in developing your original research work. Thanks.
Disclaimer: All undertaking works, records, and reports posted on this website, eprojectguide.com are the property/copyright of their individual proprietors. They are for research reference/direction purposes and the works are publicly supported. Do not present another person’s work as your own to maintain a strategic distance from counterfeiting its results. Use it as a guide and not duplicate the work in exactly the same words (verbatim). eprojectguide.com is a vault of exploration works simply like academia.edu, researchgate.net, scribd.com, docsity.com, course hero, and numerous different stages where clients transfer works. The paid membership on eprojectguide.com is a method by which the site is kept up to help Open Education. In the event that you see your work posted here, and you need it to be eliminated/credited, it would be ideal if you call us on +2348064699975 or send us a mail along with the web address linked to the work, to eprojectguide@gmail.com. We will answer to and honor each solicitation. Kindly note notification it might take up to 24 – 48 hours to handle your solicitation.